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EGFR activation leads to induction of MAPK signaling (via p38, ERK1/2) and the activation of c-Fos (Naglik et al., 2019), ultimately triggering the production of inflammatory mediators such as G-CSF and GM-CSF (Nikou et al., 2022), and the activation of the NLRP3 inflammasome leads to the release of IL-1 (Rogiers et al., 2019)

Sperm DNA fragmentation Folic acid supplementation resulted in lowering the levels of SDF in carriers of MTHFR gene TT polymorphism (106)

Along with that, eat antioxidant-rich foods

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After the co-culture, CD8 + T cells were separated from SW620 or HT29 cells by gently shaking the culture plate at 300 rpm for 3 cycles (3 min per cycle)