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Basal lipolysis has been reported to be decreased in aFABP/ALBP/aP2-null mice compared with wild-type littermates (22, 49), and stimulated lipolysis in adipocytes isolated from these mice has also been shown to be attenuated (22, 110)

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The role of the UPS in the regulation of LD proteins will be reviewed, (Figure 1) and a more in-depth review on the regulation of the LD proteome can be found by Bersuker et al