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[5] Lindson N, Theodoulou A, Ordez-Mena JM, Fanshawe TR, Sutton AJ, Livingstone-Banks J, Hajizadeh A, Zhu S, Aveyard P, Freeman SC, Agrawal S, Hartmann-Boyce J

References [edit] A Counterblaste to Tobacco (retrieved February 22, 2008) Quote: A custome lothsome to the eye, hatefull to the Nose, harmefull to the braine, dangerous to the Lungs, and in the blacke stinking fume thereof, neerest resembling the horrible Stigian smoke of the pit that is bottomelesse

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So, is nicotine a stimulant, a depressant, or both

This was performed under a multispecies coalescent model in StarBeast3 (ref