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PMCID: PMC5392015

If you have darker skin, you may need a stronger or more intensive treatment to see results

Vitamin C intake, also called ascorbic acid, has been proposed as a risk factor for kidney stones formation because vitamin C may increase urinary oxalate excretion, a type of calcium salt responsible for some stones

Notable recent developments include the first preclinical study demonstrating NNMT inhibition improves cardiac function and reduces fibrosis in a heart failure model (Li et al., 2025), a comprehensive review of NNMT as a therapeutic target for neurodegenerative disorders (Liu et al., 2025), and emerging evidence that NNMT inhibition counteracts tubular senescence and fibrosis in chronic kidney disease

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Nonetheless, if you have an allergy to vitamins, consult your doctor immediately