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Hyaluronan is the molecule in synovial fluid that is largely responsible for the viscosity of the fluid and its breakdown products can induce an inflammatory state

Eyer et al

Multiple small RCTs have shown modest but real improvements in skin elasticity and hydration

Peptides are short chains of amino acids that are vulnerable to enzymatic breakdown

ATP released by mitochondria regulates the chemotaxis of neutrophils through interacting with the purinergic receptor P2Y2 and adenosine 3 receptor at the front of the cell and the adenosine 2a receptor at the back of the cell

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