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Our recommendation

Once a multi-dose vial has been punctured for the first use, it is generally recommended to discard any remaining solution after approximately 28 days for sterility reasons, even if this falls within the original beyond-use date

Authors: We found that oral vitamin B 12 replacement at 1000 g daily was adequate to replace vitamin B 12 levels in patients with pernicious anemia

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Ustekinumab Ustekinumab is an IgG1 humanized monoclonal antibody that binds to interleukin (IL)-12 and IL-23