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Of those adults who reported using e-cigarettes in 2019, 36.9% also currently smoked cigarettes, 39.5% formerly smoked cigarettes, and 23.6% had never smoked cigarettes

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Chemical analysis of fresh and aged Australian e-cigarette liquids

Theres also evidence that people who smoke while getting cancer treatment have a worse outcome (prognosis), are less likely to respond to treatment and are more likely to have the cancer come back (recur)

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This can have serious consequences, such as paralysis