At a genome-wide significant level, three loci (ABCG2, SLC2A9, and CUX2) have been identified in association with renal urate overload, whereas four loci (ABCG2, SLC2A9, CUX2, and GCKR) have been linked to renal urate underexcretion
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10.1186/s12974-020-01749-w J
These important pathways are discussed in detail in the Amino Acid Derivatives: Neurotransmitters, Nitric Oxide, and More page
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