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In rats, both acute (4-h) and subchronic (7-day) cagrilintide treatment increased predicted Fos regulon activity in Glu4.2 Calcr/Ramp3 cells (adjusted P value ( P adj ) = 0.037 and P adj = 0.026, respectively

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This helped to show that NNMT is a key target in metabolic research. Neelakantan and colleagues then expanded research involving small-molecule NNMT inhibitors

doi: 10.12659/msm.905073 71

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Effective performance of antioxidant defence and the Gly systems corroborates enhanced tolerance to various abiotic stresses 13