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These little critters, in excess, can cause disruption to normal cellular function and can damage various parts of our cells (for our purposes cell membranes, mitochondria, & DNA of the sperm, egg, and other reproductive organ tissues)

However, most people eating varied diets aren't actually deficient

Acetylation involves the addition of an acetyl group (CHCO-) to the N-terminus, neutralizing the positive charge

1998;176:80S82S