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ACPs derived from lactoferricin B, chrysophsin-1, cecropins, and magainin-2 are peptides that have only selectivity for cancer cells and not healthy cells (145)

targeted the IP3 receptor (IP3R) channels and induced the downstream pro-apoptotic Ca 2+ -signaling pathway via synthesizing a peptide named Bcl-2 IP3 receptor disrupter-2 (BIRD-2) mimicking the structure of the BH4 domain of Bcl-2

In an additional embodiment, the enhanced viscosity formulation described herein comprises otic agent microspheres wherein the microspheres are mucoadhesive

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