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CHR: Clinical High-Risk for Psychosis
Reduced CD36 palmitoylation in LPS-stimulated CD36OE HepG2 cells promotes endocytosis and translocation of CD36 to the lysosomal membrane and autophagic SNARE proteasomal degradation, leading to impaired autophagosome-lysosome fusion and septic liver injury (164)
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GHK-Cu also apparently increased glutathione (GSH) levels, suggesting a broader upregulation of antioxidant defense mechanisms rather than action through a single pathway