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K29/K48 branched ubiquitin chains are assembled during ERAD pathways 9 , PROTAC-induced targeted degradation 10 , or ubiquitin-fusion degradation (UFD) 11,12 to promote proteasomal degradation

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

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537,538 Electrical stimulation therapies, including transcutaneous electrical nerve stimulation (TENS) and spinal cord stimulation (SCS), have demonstrated effectiveness in reducing neuropathic pain intensity and improving quality of life

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The liver contains the highest concentrations of glutathione in the body, where it neutralises harmful free radicals, supports phase II detoxification, and helps maintain cellular integrity