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The dose was divided into two doses with a taper period in which just half of the target dose was given for the first 2 weeks

Image datasets were analysed by the CT Analyser software (1.7.0.5, SkyScan, Kontich, Belgium) to evaluate bone volume (BV)

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Inhibition of NF-B Signaling One of the most well-documented effects of KPV is its ability to suppress activation of NF-B, which acts as a central regulator of inflammatory gene expression

Real-world dosing data versus clinical trial protocols Clinical trial dosage schedules represent idealized protocols under controlled conditions