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It is, however, possible that the pathological fear memories in PTSD are generalized, over-consolidated, or both, in a manner not captured by laboratory assessments of fear learning and extinction in healthy people

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Detecting microRNA binding and siRNA off-target effects from expression data

Keene and Appelbaum 2019

10 A plot of log BBB permeability (cm/sec) versus log octanol-water partition coefficient shows that increased lipophilicity directly correlates with increased membrane permeability in that the more lipid soluble a molecule is, the more readily it moves from the aqueous environment of blood across the lipid environment of the endothelial cell (EC) membrane and enters the brain

When thyroid function shifts, even subtly, the aging process can accelerate in ways that feel confusing and frustrating