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While the condition is the major cause of poor vitamin B 12 status in the elderly population, it is usually associated with atrophic gastritis, a chronic inflammation of the lining of the stomach that ultimately results in the loss of glands in the stomach (atrophy) and decreased stomach acid production (see Atrophic gastritis)

When the MTHFR enzyme is compromised, the body may struggle to properly utilize folate and B12, disrupting this crucial process

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Linked to better glucose handling in studies