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A mouse model of CRLM was established, with preliminary procedures as described for the orthotopic model

As the most abundant intracellular thiol, glutathione plays a central role in neutralizing free radicals, supporting liver function, enhancing immune cell activity, and protecting against environmental toxins [3] [4]

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Honda, Y., Kessoku, T., Sumida, Y., Kobayashi, T., Kato, T., Ogawa, Y., Nakajima, A

Glutathione works hard to protect mitochondria by eliminating these free radicals and keeps the oxidative stress in check, preventing chronic inflammation that can lead to various diseases, including rheumatoid arthritis, celiac disease, and lupus

DMSO only in matching concentrations (0.1-1%) was used as the vehicle control