Specifically, chondrocytes exposed to ferric ammonium citrate (FAC) exhibit increased expression of FTH1 and reduced levels of transferrin receptor 1 (TfR1) and hepcidin, whereas ferroportin (FPN1) expression remains unchanged (93) and in cartilage tissue from OA models (94)
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Vitamin B6 Deficiency and Disease Deficiencies of vitamin B6 are rare and usually are related to an overall deficiency of all the B-complex vitamins
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(1) FSP1/AIFM2: FSP1 was originally classified as a caspase-independent apoptosis-inducing protein, on the basis of its sequence similarity to apoptosis-inducing factor 1 (AIFM1), and was annotated as a flavoprotein with NAD(P)H oxidase activity 38
Molloy, A