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Available evidence suggests that GSH may not be an efficient protector of DNA due to its 1 net charge, which, on the basis of counter-ion condensation and co-ion depletion phenomena, may allow its dissociation from DNA [61]
doi: 10.1080/1744666X.2018.1450141 143 DornerTShockAGoldenbergDMLipskyPE
This means every single tick mark on the syringe is equivalent to a 50mcg dose of AOD 9604
In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected
Lin Y, Caldwell GW, Li Y, Lang W, Masucci J