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In retrospect, the article can be seen as one of the foundation stones of what is now often called the ascorbateglutathione pathway, or FoyerHalliwellAsada pathway (Foyer and Kunert 2024)

Acknowledgements Portions of the MS-based proteomics work described herein were performed at the Environmental Molecular Sciences Laboratory (grid.436923.9), a US Department of Energy (DOE) National Scientific User Facility located at the Pacific Northwest National Laboratory (PNNL)

Bandeira SDM, Da Fonseca LJS, Guedes GDS, Rabelo LA, Goulart MO, Vasconcelos SML

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Finally, the DNA-binding ability of some transcription factors is directly influenced by ROS

[21] [22] [23] FOXO4 activates the cell cycle dependent kinase inhibitor, P27, which in turn prevents tumors from progressing into G1