And then I looked up the notes and then it hit me
A number of studies have shown that arterial stiffness increases acutely after cigarette or cigar smoking as measured by AIx, cfPWV, brPWV or crPWV
Using too much nicotine, especially if you're not accustomed to it, can lead to an uncomfortable nicotine "high." This occurs if you consume more nicotine than your body can take, often from using higher-strength products or taking multiple doses too close together
[9] Tobacco was introduced elsewhere in continental Europe more easily
Manufacturers can use any legal, natural or artificial ingredient they wish from a long list of approved additives
Why do these states rely the most on alcohol, tobacco, and gambling taxes