Immune modulation: Peptides can reduce pathological inflammation without broadly suppressing immune function
Choong et al, 2005)
While GHK-Cu is a cosmetic ingredient, no formal safety data exists for use during pregnancy or breastfeeding
In 1981, for example, a paper published in the International Journal of Clinical Pharmacology, Therapy, and Toxicology described a trial with six volunteers who experienced immediate sleep pressure after intravenous DSIP infusion, as well as increased sleep time, decreased sleep onset, and better sleep efficiency without any sedative effects.13 Three years later, two other human trials across ten test subjects with insomnia found that DSIP administration yielded statistically significant improvements in several key sleep measures fewer sleep arousals, greater sleep efficiency, and increased REM, spindle, and slow-wave sleep.14 The above studies had shortcomings, namely their very small sample sizes, but the sleep-improving effects in cases of insomnia point to DSIPs potential to live up to its name
It occupies a grey area: legal to purchase for research purposes, but it cannot be sold as a medicine or for human consumption
However, whether oral bioavailability translates meaningfully to humans has not been established in clinical trials
