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Crystal structure of SnCE1-SUMO1-PA reveals preference to act as deSUMOylase To unravel the molecular mechanisms underlying the preference of SnCE1 towards SUMO chains compared to Ub chains we next performed further structure-function analyses (Fig

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When rheumatoid arthritis damages and changes the synovium, your joints lose that vital lubricating fluid, leading to further pain, damage, and loss of mobility