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The vast majority of trials showed improved skin elasticity and a reduction in facial wrinkles following treatment

Results were reportedly submitted to ClinicalTrials.gov on May 23, 2016, but the study itself is listed as canceled, which indicates the study sponsor or investigator recalled a submission of study results before quality control review took place

A significant study observed notably reduced vitamin C levels in patients with atopic dermatitis, recording plasma vitamin C concentrations between 0.11-0.55 mg/dL (6-31 umol/L), well below the optimal concentration of over 1.06 mg/dL (60 umol/L)

10.1080/07853890.2024.2337871 50 LiangY.ZhangC.WeiH.DuH.ZhangG.YangY.et al (2022)

subtilis spore-based paramyosin, lower than 13.2 in the control group (329)

Upon admission, a safety call will be placed to notify loved ones