In carrageenan-induced paw edema models and in CFA (complete Freund's adjuvant) arthritis models in rats, BPC-157 administration significantly reduced TNF-, IL-6, and IL-1 levels in local tissue samples compared to saline controls
Zhang Q, Zhang Y, Jing L, Zhao H
Gene expression analysis To obtain further insight into the mechanisms of BPC-157 participation in cell signal transduction, we carried out a quantitative real-time PCR using a Signal Transduction PathwayFinder RT 2 Profiler PCR Array, which contained a set of primers for 84 key genes representative of 18 different signal transduction pathways
By enhancing fibroblast migration to injury sites, BPC-157 accelerates the production of new structural material needed for tissue repair
Creatine is a compound you naturally have in your body
TB-500s most extensively studied tissue applications reflect the original characterisation of thymosin beta-4 as a cardiac repair mediator with cardiac ischaemia and myocardial infarction models representing the most documented research context for TB-500 biology