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In our opinion, unraveling the diverse mechanoresponses of breast tumor cells will facilitate the development of new therapeutic approaches to combat breast cancer progression

DOI: 10.1038/s41389-017-0025-3 55

While the precise molecular intermediaries and signaling pathways remain to be clarified, ipamorelins influence on bone-associated endocrine loops (involving growth hormone and maybe local IGF-I) is plausibly central, potentially altering the balance between bone-forming and bone-remodeling processes at the tissue level