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By inhibiting NNMT, it alters the balance of S-adenosylmethionine (SAM) and nicotinamide metabolism, affecting DNA methylation patterns and histone modifications

10.1007/s10067-014-2736-6 [DOI] [PubMed] [Google Scholar] 3.Siracusa R, Paola RD, Cuzzocrea S, Impellizzeri D

Department of Health and Human Services, 26 Mar

Professional guidance helps: Determine appropriate dosing schedules Monitor B12 levels regularly Adjust protocols based on training phases Integrate B12 with other aspects of training Healthcare providers can also help athletes identify signs of B12 deficiency and adjust supplementation accordingly

H., Bjrke-Monsen A.-L., Brito A., Guant J.-L., Miller J

(October 2004)