This results in activated T cells & B cells that produce an anti-citrulline inflammatory response that affects the joints, resulting in swelling and degradation of both cartilage and bone (Schur & Firestein, 2012) as illustrated in Figures 3, 4 & 5
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GreenLight laser, iTind, Rezum, HoLEP, TURP (Transurethral resection of the prostate) or procedures to hold the prostate away from the prostatic urethra such as Urolift

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This is a clinical and medicolegal imperative
At the same time, certain peptides can influence stem cell activity, improving survival and effectiveness