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Rotate your injection sites with each dose to prevent lipohypertrophy (thickened fat deposits) that can develop from repeated punctures in the same spot

Bile drains to the duodenum via the minor papilla (inset)

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The body regulates B12 absorption through intrinsic factor, a protein produced in the stomach that binds to B12 and facilitates its uptake in the terminal ileum

The likelihood and intensity depend on your dose and other factors specific to you

They also monitor treatment closely and adjust the regimen as needed