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Despite promising Phase 2 results and an excellent safety profile, the compound could not demonstrate sufficient efficacy in the larger confirmatory trial to justify the investment required for continued pharmaceutical development toward regulatory approval

There is also some ambiguity in the evidence exploring the ability of nutritional interventions to enhance glutathione status, with more research needed to clarify optimal dose and delivery forms as well as identification of sub-groups of individuals most likely to respond to particular nutrients or foods

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these constructs inhibited tumor progression by reprogramming IL4R-high and M2-polarized TAMs to an M1-like phenotype 39

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For researchers, this consolidation creates a paradoxically better environment: the average quality of available suppliers has increased, because the market-clearing event removed the least compliant, least transparent, and most risk-prone operators