Monitoring Progress Effectively: Rather than relying solely on scale weight, which can be misleading due to muscle preservation and fluid fluctuations, comprehensive progress tracking should include body composition analysis (DEXA scan, bioelectrical impedance, or skinfold measurements), circumference measurements (waist, hips, thighs, arms), progress photos taken in consistent lighting and positioning, and subjective measures like energy levels, appetite patterns, and how clothing fits
Human data are limited and mixed: Clinical studies have largely assessed safety and metabolism, while weight-related outcomes were modest and inconsistent
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Obeid R, Andrs E, eka R, Hooshmand B, Guant-Rodriguez RM, Prada GI, Sawek J, Traykov L, Ta Van B, Vrkonyi T, Reiners K, The Vitamin B Consensus Panelists Group
N Engl J Med 341 : 785792 Clemmons DR (1993) Use of growth hormone and insulin-like growth factor I in catabolism that is induced by negative energy balance
