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Consequently, the plasma half-life of the GLP-1 albumin fusion was reduced from 1.3 days to 0.9 days in the human FcRn Tg32 mice

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PMID 34509090

One mechanism

Preexisting Health Conditions Although BPC-157 is non-hormonal and generally well-tolerated, individuals with certain health conditions may be more sensitive to its effects

CHIP and HSPs interact with -APP in a proteasome-dependent manner and influence A metabolism