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Early work showed that Put, Spd, and Spm are enriched at synaptic terminals, but concluded that these polyamines are not themselves released as neurotransmitters (Seiler and Deckardt, 1976)

Hence, a long heparin polymer could crosslink HGF I and II by simultaneous binding both HGFs and thereby stabilize the c-MET II-HGF I-HGF II tripartite interaction (Fig

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Ott B, Skurk T, Hastreiter L, et al

Clinical studies show 20% to 30% improvement in skin firmness after twelve weeks of topical use