It is not designed for human or veterinary use, consumption, injection, or any other application involving living subjects
Prodrugs are conjugated to RNA nanoparticles via efficient click chemistry, creating an ester linker that is cleaved by esterases in tumor tissues or cells, allowing the prodrugs to return back to their original structures and chemistry upon delivery and release, minimizing toxicity
This gentle introduction allows the powder to dissolve passively, preserving its molecular integrity
Be gentle to avoid shaking or disturbing the contents inside
Five of these compounds had commercially available authentic reference standards available (Sigma-Aldrich, US
Its important to note that vitamin B12 is water-soluble, so excess amounts are typically excreted in the urine