In summary, ROS plays a multifaceted regulatory role in amino acid metabolism, encompassing synthesis and modification, thereby exerting a profound impact on cell function and survival
Glutathione, even if it improves mitochondrial ATP production by 510%, does not create a caloric deficit
Lipid metabolism pathways, particularly steroid hormone biosynthesis and cholesterol metabolism, were highly enriched across all three iHLO development phases, indicating the organoids capacity to process lipids, especially cholesterol
doi: 10.1093/aje/kwp315
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