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10,11 The ovaries are also made up of theca and granulosa cells, responsible for secreting estrogen, progesterone, androgens (male hormones), and other factors that regulate follicular activation and maturation

Published clinical evidence includes a Phase 1b multiple-ascending-dose trial reported by Enebo and colleagues (Lancet, 2021) and a Phase 2 trial in type 2 diabetes reported by Frias and colleagues (Lancet, 2023), both studying cagrilintide together with semaglutide

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Furthermore, the incorporation of Met residues also functioned as redox modulators that restored the metabolic homeostasis 41,43