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These effects of Pycnogenol on joints can be explained by previous findings, showing that regular intake of Pycnogenol leads to a potent decrease of pro-inflammatory markers like NF-B and COX-enzymes, as well as a decline in the release of matrix metallopeptidase (MMP) enzymes, that are responsible for destroying cartilage in joints (1518, 71)

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Jiang and Zhu, 2015)

Experimental Materials Salicylic acid (SA, purity 98.0%), cetyltrimethylammonium p-toluenesulfonate (CTAT), bis(trimethoxysilylpropyl)disulfide (BTSPD), tetraethyl orthosilicate ester (TEOS), ammonium nitrate, and 3-Aminopropyltrimethoxysilane (APS) were purchased from Tianjin Heowns Biochemical Technology Co., Ltd

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