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Murine models of blood storage have identified genetic factors that contribute to the altered capacity of stored RBCs ( e.g., the ferrireductase STEAP3) 11,12 and mitigate oxidative damage ( e.g., activation of the pentose phosphate pathway by G6PD to generate reducing equivalents) 1315

Meanwhile, hypoxia-responsive hydrogels containing azobenzene or nitroimidazole moieties undergo bond cleavage under low O, triggering release of oxygen carriers or hypoxia-activated prodrugsoffering a direct countermeasure to the hypoxiaradioresistance axis [209]

Ikeda T, Iwata K, Tanaka Y

Your body converts NAC directly into glutathione

Boulet C, Doerig CD, Carvalho TG

** The result depends on individual metabolism