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A meta-analysis indicated that vitamin E supplementation effectively declined T, LH, LDL, and TG levels while increasing progesterone (P) and FSH concentrations in PCOS patients (21)

One outcome is the accumulation of the oncometabolite -ketoglutarate, feeding the production of citrate and acetyl-CoA

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Potential benefits for the gut include: Reducing intestinal inflammation in IBD and colitis Modulating immune response to prevent overactivation Decreasing harmful bacterial overgrowth and supporting a healthier gut microbiome Enhancing epithelial barrier function to prevent leaky gut How it works: KPV helps regulate cytokine production, balancing the immune systems activity so it calms inflammation without shutting down natural defenses

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Milk thistle (a liver-supporting herb) to help maintain glutathione levels