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Vitamin B12 shots are generally considered to be safe and have no major side effects

Rotchell J and Ostrander G 2003 Molecular markers of endocrine disruption in aquatic organisms

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The authors reported that AOD-9604 stimulated lipolysis in isolated adipocytes and that chronic daily treatment in obese Zucker rats produced reductions in body weight gain of more than 50% relative to untreated controls over the treatment period, without effects on insulin sensitivity or IGF-1 levels [3]

The dose is 100200 mg IM, two or three times weekly

Although OA remains incurable, HA viscosupplements, like Cingal injections, have shown promising results for alleviating symptoms, especially in the knee and hip joints