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"Tau aggregation inhibitor therapy: An exploratory phase 2 study of leuco-methylthioninium bis(hydromethanesulfonate) in mild or moderate Alzheimers disease." Journal of Alzheimers Disease, 58(4), 1049-1065
Suitable for mild cases and maintenance protocols
Given that both diet composition and adiposity can each substantially impact the gut microflora in obese mice 24 , we conducted a secondary endpoint study using animals given the same series of diets to test the hypothesis that NNMTi treatment combined with LD, but not LD alone, shifts the cecal microbiome profile of obese animals to be similar to age-matched LD controls that were never given a high-fat diet