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Blocking NNMT activity has been shown in research settings to influence body composition, leading to reduced adipocyte size, alterations in fat mass, and measurable changes in plasma biomarkers such as glucose and cholesterol

Deficiency can cause numbness, tingling, and cognitive fog

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Overdosing can lead to elevated B12 levels and potential side effects, while underdosing may not adequately address symptoms

(PubMed) Sawka AM, Ray JG, Yi Q, Josse RG, Lonn E

Additive effects of intra-articular injection of growth hormone and hyaluronic acid in rabbit model of collagenase-induced osteoarthritis