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have found that among the skeletal muscle biopsies of 28 ASD children with mitochondrial diseases, 50% had defects of complex I, 18% had combined defects of complex I and III, another 18% were identified with the combined defects of complexes I, III, and IV, and 14% were with defects of complex V [74]

Mast cells are innate immune cells that release inflammatory mediators, including histamine, when they detect a threat

Grant CM (2001)

The normal cellular function of C9orf72 is related to vesicular trafficking and autophagy (Farg et al., 2014) whereas SOD1 is an antioxidant enzyme that mediates detoxification of the superoxide anion radical (

The succinate-ubiquinone oxidoreductase subunit A (SDHA) is part of complex II of the respiratory chain and catalyzes the reaction of succinate to fumarate in the tricarboxylic acid cycle