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In pharmaceutical applications, coupled systems such as SPESFE or SPMEGCMS are used for drug profiling, bioavailability assessments, and impurity detection

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Evans-blue vascular permeability assay To assess vascular permeability, animals (n=9-9) received 50 mg/kg Evans blue (Reanal, Hungary, dissolved in physiological saline at a concentration of 2.5%) via a femoral venous catheter

Paediatr 2004, 62, 7782

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