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Synaptic pruning and axonal myelination during adolescence are permanent structural processes: substance-induced disruptions during these windows produce lasting changes in prefrontal-striatal connectivity that increase impulsivity and reward sensitivity into adulthood and cannot be fully reversed

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It is also crucial to consider the potential health risks associated with e-cigarette use and to follow best practices, such as avoiding underage use, purchasing from reputable sources, and adhering to product safety guidelines

PMID: 34938579

"Most smokers want to quit