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PMC 5788147

Following enucleation, eyes were fixed, frozen, sectioned and H&E stained to visualize the ONL

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These approaches range from repurposing existing metabolic modulators and antioxidants to developing gene-editing technologies, offering a promising adjunctive avenue to improve the long-term well-being of PLWH

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This reduction in GSH levels resulted in the inhibition of sarcoplasmic reticulum Ca2 + -ATPase (SERCA) activation, leading to elevated cytosolic Ca 2+ levels and CaMKII phosphorylation