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During the prenatal and postnatal periods of development, there are transient regional patterns of increased nAChR subunit expression that occur during critical periods of neural development involving synaptogenesis, neurogenesis, apoptosis, and migration [29]

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1 2 3 4 "Minimum Ages of Legal Access for Tobacco in the United States From 1863 to 2015"

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[11] The CDC also notes that, "However, because low-income groups are more responsive to price increases, increasing the real price of cigarettes can reduce cigarette consumption among low income smokers by a greater percentage than among higher income smokers, and thereby diminish socioeconomic smoking disparities