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Its most important function is vasodilation, meaning it relaxes the inner muscles of the blood vessels, causing them to widen and increase circulation

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These cells integrate into the ovarian tissue, modulating the expression of essential cellular markers by significantly increasing epithelial markers (cytokeratin 7) and estrogen receptors (ER), while concurrently decreasing mesenchymal markers (fibronectin and vimentin), thus reversing the ovarian fibrosis associated with POF

[DOI] [PubMed] [Google Scholar] 15.Miladinovi ., Muheim C., Bauer S., Spinnler A., Noain D., Bandarabadi M., Gallusser B., Krummenacher G., Baumann C., Adamantidis A

PMID: 31384691

Research suggests it can be used to explore epithelial barrier integrity, extracellular matrix remodeling, and cell migration in preclinical in-vitro and animal experiments