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This difference helps explain why Melanotan 1 mainly affects pigmentation, while Melanotan 2 has broader effects

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An absolute fold change of 2 or more and 0.05 adjusted P-value were set as cutoff to evaluate the significance of gene expression differences of raw data

MSC-Exos, however, persistently modulate the cellular microenvironment, promoting tissue repair alongside ferroptosis suppression [104]

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