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It is also induced during endoplasmic reticulum stress, regulated by the ATF4-CHOP branch of the unfolded protein response, and elicits an apoptotic response 40

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Abstract Glutathione- S -transferases (GSTs) are a family of Phase II detoxification enzymes that catalyse the conjugation of glutathione (GSH) to a wide variety of endogenous and exogenous electrophilic compounds

Reduced glutathione (GSH) is used by glutathione peroxidase to detoxify hydrogen peroxide and in the precess is converted to oxidized glutathione (GSSG)

Healthy mitochondria are essential for producing the energy required for cellular repair, regeneration, and the synthesis of structural proteins like collagen and elastin